{"id":24780,"date":"2023-01-11T17:26:37","date_gmt":"2023-01-11T10:26:37","guid":{"rendered":"https:\/\/shopbiz.vn\/?p=1325"},"modified":"2023-01-11T17:26:37","modified_gmt":"2023-01-11T10:26:37","slug":"folate-vitamin-b9-la-gi-tac-dung-va-lieu-dung-folate-voi-co-the","status":"publish","type":"post","link":"https:\/\/elysostore.com\/vi\/folate-vitamin-b9-la-gi-tac-dung-va-lieu-dung-folate-voi-co-the\/","title":{"rendered":"Folate (vitamin B9) l\u00e0 g\u00ec? T\u00e1c d\u1ee5ng v\u00e0 li\u1ec1u d\u00f9ng Folate v\u1edbi c\u01a1 th\u1ec3"},"content":{"rendered":"
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Folate l\u00e0 g\u00ec? <\/strong>Folate hay c\u00f2n g\u1ecdi l\u00e0 vitamin B9 r\u1ea5t quan tr\u1ecdng trong vi\u1ec7c h\u00ecnh th\u00e0nh t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u v\u00e0 cho s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a t\u1ebf b\u00e0o kh\u1ecfe m\u1ea1nh. Axit folic – phi\u00ean b\u1ea3n nh\u00e2n t\u1ea1o c\u1ee7a vitamin B9 – r\u1ea5t c\u1ea7n thi\u1ebft cho s\u1ef1 ph\u00e1t tri\u1ec3n th\u00edch h\u1ee3p c\u1ee7a c\u01a1 th\u1ec3 con ng\u01b0\u1eddi. Khi m\u1ed9t ch\u1ebf \u0111\u1ed9 \u0103n thi\u1ebfu th\u1ef1c ph\u1ea9m gi\u00e0u folate ho\u1eb7c axit folic c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn thi\u1ebfu h\u1ee5t folate, g\u00e2y ra m\u1ed9t s\u1ed1 \u1ea3nh h\u01b0\u1edfng t\u1edbi s\u1ee9c kh\u1ecfe.<\/p>\n<\/div>\n

1. Folate (Vitamin B9) l\u00e0 g\u00ec?<\/h2>\n
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Vitamin B9<\/b>\u00a0hay\u00a0Folate<\/b>, tr\u01b0\u1edbc \u0111\u00e2y g\u1ecdi l\u00e0 folacin, l\u00e0 thu\u1eadt ng\u1eef chung cho c\u1ea3 folate th\u1ef1c ph\u1ea9m t\u1ef1 nhi\u00ean v\u00e0 axit folic, d\u1ea1ng monoglutamate oxy h\u00f3a ho\u00e0n to\u00e0n c\u1ee7a vitamin \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong th\u1ef1c ph\u1ea9m b\u1ed5 sung<\/a> v\u00e0 th\u1ef1c ph\u1ea9m t\u0103ng c\u01b0\u1eddng. \u0110\u00e2y l\u00e0 m\u1ed9t\u00a0vitamin nh\u00f3m B<\/b><\/a>\u00a0quan tr\u1ecdng cho s\u1ef1 ph\u00e1t tri\u1ec3n v\u00e0 trao \u0111\u1ed5i ch\u1ea5t c\u1ee7a t\u1ebf b\u00e0o.<\/p>\n

Vitamin B9<\/b>\u00a0v\u00e0 axit folic c\u00f3 t\u00e1c d\u1ee5ng t\u01b0\u01a1ng t\u1ef1.\u00a0Vitamin B9<\/b>\u00a0\u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y t\u00ecm th\u1ea5y t\u1ef1 nhi\u00ean trong th\u1ef1c ph\u1ea9m.\u00a0Axit folic<\/b><\/a>\u00a0l\u00e0 phi\u00ean b\u1ea3n nh\u00e2n t\u1ea1o b\u1ed5 sung v\u00e0 th\u00eam v\u00e0o th\u1ef1c ph\u1ea9m.<\/p>\n

T\u1eeb n\u0103m 1998, axit folic \u0111\u00e3 \u0111\u01b0\u1ee3c th\u00eam v\u00e0o ng\u0169 c\u1ed1c, b\u1ed9t m\u00ec, b\u00e1nh m\u00ec, m\u00ec \u1ed1ng, c\u00e1c m\u1eb7t h\u00e0ng b\u00e1nh… Th\u1ef1c ph\u1ea9m c\u00f3 nhi\u1ec1u\u00a0folate t\u1ef1 nhi\u00ean<\/b>\u00a0bao g\u1ed3m c\u00e1c lo\u1ea1i rau l\u00e1 (nh\u01b0 rau bina, b\u00f4ng c\u1ea3i xanh v\u00e0 rau di\u1ebfp), \u0111\u1eadu b\u1eafp, m\u0103ng t\u00e2y, tr\u00e1i c\u00e2y (nh\u01b0 chu\u1ed1i, d\u01b0a, v\u00e0 chanh) \u0111\u1eadu, men, n\u1ea5m, th\u1ecbt (nh\u01b0 gan v\u00e0 th\u1eadn b\u00f2), n\u01b0\u1edbc cam v\u00e0 n\u01b0\u1edbc \u00e9p c\u00e0 chua.<\/p>\n

Axit folic<\/b>\u00a0c\u0169ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong nhi\u1ec1u t\u00ecnh tr\u1ea1ng b\u1ec7nh kh\u00e1c bao g\u1ed3m \u0111au d\u00e2y th\u1ea7n kinh trong b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng, b\u1ec7nh tim, m\u1ea5t tr\u00ed nh\u1edb v\u00e0 nhi\u1ec1u b\u1ec7nh kh\u00e1c.<\/p>\n

Axit folic<\/b>\u00a0th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p v\u1edbi c\u00e1c\u00a0vitamin B<\/b>\u00a0kh\u00e1c. L\u01b0\u1ee3ng folate h\u00e0ng ng\u00e0y \u0111\u01b0\u1ee3c khuy\u00ean d\u00f9ng cho ng\u01b0\u1eddi l\u1edbn l\u00e0 400 microgam (mcg). Ph\u1ee5 n\u1eef tr\u01b0\u1edfng th\u00e0nh \u0111ang c\u00f3 k\u1ebf ho\u1ea1ch mang thai ho\u1eb7c c\u00f3 th\u1ec3 mang thai n\u00ean \u0111\u01b0\u1ee3c khuy\u00ean n\u00ean u\u1ed1ng 400 \u0111\u1ebfn 800 mcg axit folic m\u1ed7i ng\u00e0y.<\/p>\n

2. Vitamin B9 c\u00f3 t\u00e1c d\u1ee5ng g\u00ec?<\/h2>\n
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Ng\u0103n ng\u1eeba s\u1ef1 ph\u00e1t tri\u1ec3n ung th\u01b0 v\u00fa<\/h3>\n

B\u1ed5 sung vitamin B9 trong ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m nguy c\u01a1 ph\u00e1t tri\u1ec3n\u00a0ung th\u01b0 v\u00fa\u00a0\u1edf nh\u1eefng ph\u1ee5 n\u1eef c\u0169ng \u0103n nhi\u1ec1u methionine,\u00a0vitamin B12\u00a0(cyanocobalamin) ho\u1eb7c\u00a0vitamin B6\u00a0(pyridoxine)<\/p>\n

Ng\u0103n ng\u1eeba nguy c\u01a1 d\u1ecb t\u1eadt b\u1ea9m sinh<\/h3>\n

B\u1ed5 sung\u00a0axit folic<\/b>\u00a0c\u00f3 th\u1ec3 ng\u0103n ng\u1eeba d\u1ecb t\u1eadt b\u1ea9m sinh c\u1ee7a \u1ed1ng th\u1ea7n kinh. Ph\u1ee5 n\u1eef mang thai c\u1ea7n u\u1ed1ng vitamin B9 tr\u01b0\u1edbc khi sinh h\u00e0ng ng\u00e0y – th\u1eddi gian u\u1ed1ng l\u00fd t\u01b0\u1edfng l\u00e0 b\u1eaft \u0111\u1ea7u ba th\u00e1ng tr\u01b0\u1edbc khi th\u1ee5 thai – \u0111\u1ea3m b\u1ea3o gi\u00fap m\u1eb9 b\u1ea7u c\u00f3 \u0111\u1ee7 ch\u1ea5t dinh d\u01b0\u1ee1ng thi\u1ebft y\u1ebfu n\u00e0y.<\/p>\n

\u0110i\u1ec1u tr\u1ecb thi\u1ebfu folate<\/h3>\n

V\u1edbi nh\u1eefng ng\u01b0\u1eddi thi\u1ebfu folate c\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng b\u1ed5 sung\u00a0axit folic<\/b>\u00a0\u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n

Gi\u1ea3m nguy c\u01a1 m\u1eafc b\u1ec7nh tim v\u00e0 \u0111\u1ed9t qu\u1ef5<\/h3>\n

Axit folic k\u1ebft h\u1ee3p v\u1edbi vitamin B6 v\u00e0 B12 \u0111\u1ec3 ki\u1ec3m so\u00e1t n\u1ed3ng \u0111\u1ed9 homocysteine \u200b\u200bcao trong m\u00e1u. N\u1ed3ng \u0111\u1ed9 homocysteine \u200b\u200bt\u0103ng cao c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 m\u1eafc c\u00e1c b\u1ec7nh v\u1ec1 tim v\u00e0 m\u1ea1ch m\u00e1u (b\u1ec7nh tim m\u1ea1ch).<\/p>\n

Gi\u1ea3m nguy c\u01a1 m\u1eafc ung th\u01b0<\/h3>\n

M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u cho th\u1ea5y folate c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m nguy c\u01a1 m\u1eafc c\u00e1c b\u1ec7nh ung th\u01b0 kh\u00e1c nhau.<\/p>\n

\u0110i\u1ec1u tr\u1ecb phi\u1ec1n mu\u1ed9n v\u00e0 sa s\u00fat tr\u00ed tu\u1ec7<\/h3>\n

Axit folic \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng hi\u1ec7u qu\u1ea3 trong \u0111i\u1ec1u tr\u1ecb\u00a0tr\u1ea7m c\u1ea3m<\/b>\u00a0v\u00e0 ng\u0103n ng\u1eeba ch\u1ee9ng\u00a0m\u1ea5t tr\u00ed nh\u1edb<\/b>.<\/p>\n

H\u1ed7 tr\u1ee3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh th\u1eadn nghi\u00eam tr\u1ecdng (b\u1ec7nh th\u1eadn giai \u0111o\u1ea1n cu\u1ed1i ho\u1eb7c ESRD)<\/h3>\n

Kho\u1ea3ng 85% nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh th\u1eadn nghi\u00eam tr\u1ecdng c\u00f3 n\u1ed3ng \u0111\u1ed9 homocysteine \u200b\u200bcao. N\u1ed3ng \u0111\u1ed9 homocysteine \u200b\u200bcao c\u00f3 li\u00ean quan \u0111\u1ebfn b\u1ec7nh tim v\u00e0 \u0111\u1ed9t qu\u1ef5. U\u1ed1ng\u00a0axit folic<\/b>\u00a0l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 homocysteine \u200b\u200b\u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ecb b\u1ec7nh th\u1eadn nghi\u00eam tr\u1ecdng. Tuy nhi\u00ean, b\u1ed5 sung axit folic kh\u00f4ng l\u00e0m gi\u1ea3m nguy c\u01a1 m\u1eafc c\u00e1c b\u1ec7nh li\u00ean quan \u0111\u1ebfn b\u1ec7nh tim.<\/p>\n

Gi\u1ea3m l\u01b0\u1ee3ng homocysteine \u200b\u200bcao trong m\u00e1u (hyperhomocystein)<\/h3>\n

N\u1ed3ng \u0111\u1ed9 homocysteine \u200b\u200bcao c\u00f3 li\u00ean quan \u0111\u1ebfn b\u1ec7nh tim v\u00e0 \u0111\u1ed9t qu\u1ef5. U\u1ed1ng axit folic l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9\u00a0homocysteine<\/b>\u00a0\u200b\u200bt\u1eeb 20% \u0111\u1ebfn 30% \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 m\u1ee9c homocysteine \u200b\u200bb\u00ecnh th\u01b0\u1eddng \u0111\u1ebfn t\u0103ng nh\u1eb9. Khuy\u1ebfn c\u00e1o r\u1eb1ng nh\u1eefng ng\u01b0\u1eddi c\u00f3 m\u1ee9c homocysteine \u200b\u200bl\u1edbn h\u01a1n 11 micromole\/L b\u1ed5 sung axit folic v\u00e0 vitamin B12.<\/p>\n

Gi\u1ea3m \u0111\u1ed9c t\u00ednh g\u00e2y ra b\u1edfi thu\u1ed1c methotrexate<\/h3>\n

U\u1ed1ng\u00a0axit folic<\/b>\u00a0d\u01b0\u1eddng nh\u01b0 l\u00e0m gi\u1ea3m bu\u1ed3n n\u00f4n v\u00e0 n\u00f4n, \u0111\u00f3 l\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 c\u00f3 c\u1ee7a \u0111i\u1ec1u tr\u1ecb methotrexate.<\/p>\n

D\u1ecb t\u1eadt b\u1ea9m sinh c\u1ee7a n\u00e3o v\u00e0 c\u1ed9t s\u1ed1ng (d\u1ecb t\u1eadt b\u1ea9m sinh \u1ed1ng th\u1ea7n kinh)<\/h3>\n

Axit folic<\/b>\u00a0khi mang thai l\u00e0m gi\u1ea3m nguy c\u01a1 d\u1ecb t\u1eadt \u1ed1ng th\u1ea7n kinh. Ph\u1ee5 n\u1eef mang thai n\u00ean u\u1ed1ng 600-800 mcg axit folic m\u1ed7i ng\u00e0y t\u1eeb ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng ho\u1eb7c ch\u1ea5t b\u1ed5 sung b\u1eaft \u0111\u1ea7u 1 th\u00e1ng tr\u01b0\u1edbc khi mang thai v\u00e0 trong khi mang thai. Ph\u1ee5 n\u1eef mang thai c\u00f3 ti\u1ec1n s\u1eed d\u1ecb t\u1eadt b\u1ea9m sinh \u1ed1ng th\u1ea7n kinh n\u00ean u\u1ed1ng 4000 mcg axit folic m\u1ed7i ng\u00e0y.<\/p>\n

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Gi\u1ea3m nguy c\u01a1 m\u1eafc b\u1ec7nh v\u1ec1 m\u1eaft d\u1eabn \u1edf ng\u01b0\u1eddi l\u1edbn tu\u1ed5i<\/h3>\n

Ng\u01b0\u1eddi l\u1edbn tu\u1ed5i l\u00e0 \u0111\u1ed1i t\u01b0\u1ee3ng d\u1ec5 g\u1eb7p c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 m\u1eaft nh\u01b0\u00a0tho\u00e1i h\u00f3a \u0111i\u1ec3m v\u00e0ng<\/b>\u00a0li\u00ean quan \u0111\u1ebfn tu\u1ed5i t\u00e1c ho\u1eb7c AMD. Axit folic v\u1edbi c\u00e1c vitamin kh\u00e1c bao g\u1ed3m vitamin B6 v\u00e0 vitamin B12 gi\u00fap gi\u1ea3m nguy c\u01a1 m\u1ea5t th\u1ecb l\u1ef1c li\u00ean quan \u0111\u1ebfn tu\u1ed5i t\u00e1c.<\/p>\n

Gi\u1ea3m huy\u1ebft \u00e1p cao<\/h3>\n

Nghi\u00ean c\u1ee9u cho th\u1ea5y u\u1ed1ng\u00a0axit folic<\/b>\u00a0h\u00e0ng ng\u00e0y trong \u00edt nh\u1ea5t 6 tu\u1ea7n gi\u00fap gi\u1ea3m huy\u1ebft \u00e1p \u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ecb\u00a0t\u0103ng huy\u1ebft \u00e1p<\/b>. Nh\u01b0ng u\u1ed1ng axit folic nh\u01b0 m\u1ed9t lo\u1ea1i thu\u1ed1c d\u01b0\u1eddng nh\u01b0 kh\u00f4ng l\u00e0m gi\u1ea3m huy\u1ebft \u00e1p h\u01a1n so v\u1edbi ch\u1ec9 d\u00f9ng thu\u1ed1c huy\u1ebft \u00e1p.<\/p>\n

Ch\u00fang ta n\u00ean b\u1ed5 sung\u00a0folate<\/b>\u00a0t\u1eeb c\u00e1c lo\u1ea1i th\u1ef1c ph\u1ea9m. M\u1ed9t ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng c\u1ea7n c\u00e2n b\u1eb1ng t\u1ea5t c\u1ea3 nh\u1eefng ch\u1ea5t dinh d\u01b0\u1ee1ng c\u01a1 th\u1ec3 c\u1ea7n. Tuy nhi\u00ean, b\u1ed5 sung axit folic \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb cho nh\u1eefng ph\u1ee5 n\u1eef \u0111ang c\u00f3 k\u1ebf ho\u1ea1ch mang thai, c\u00f3 th\u1ec3 mang thai, \u0111ang mang thai ho\u1eb7c \u0111ang cho con b\u00fa.<\/p>\n<\/div>\n

3. Li\u1ec1u d\u00f9ng vitamin B9<\/h2>\n
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3.1 Khi u\u1ed1ng b\u1eb1ng \u0111\u01b0\u1eddng mi\u1ec7ng<\/h3>\n

Vitamin B9 hay axit folic<\/b>\u00a0an to\u00e0n cho h\u1ea7u h\u1ebft m\u1ecdi ng\u01b0\u1eddi khi u\u1ed1ng. H\u1ea7u h\u1ebft ng\u01b0\u1eddi l\u1edbn kh\u00f4ng g\u1eb7p b\u1ea5t k\u1ef3 t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0o khi s\u1eed d\u1ee5ng v\u1edbi li\u1ec1u d\u01b0\u1edbi 1 mg m\u1ed7i ng\u00e0y. S\u1eed d\u1ee5ng axit folic v\u1edbi li\u1ec1u 800 mcg \u0111\u1ebfn 1,2 mg m\u1ed7i ng\u00e0y c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 \u0111au tim \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 v\u1ea5n \u0111\u1ec1 v\u1ec1 tim.<\/p>\n

Axit folic\u00a0kh\u00f4ng \u0111em l\u1ea1i hi\u1ec7u qu\u1ea3 khi u\u1ed1ng li\u1ec1u l\u01b0\u1ee3ng l\u1edbn v\u1edbi th\u1eddi gian d\u00e0i. S\u1eed d\u1ee5ng li\u1ec1u axit folic l\u1edbn h\u01a1n 1 mg m\u1ed7i ng\u00e0y c\u00f3 th\u1ec3 g\u00e2y ra chu\u1ed9t r\u00fat b\u1ee5ng,\u00a0ti\u00eau ch\u1ea3y, ph\u00e1t ban, r\u1ed1i lo\u1ea1n gi\u1ea5c ng\u1ee7, kh\u00f3 ch\u1ecbu, nh\u1ea7m l\u1eabn, bu\u1ed3n n\u00f4n, \u0111au d\u1ea1 d\u00e0y, thay \u0111\u1ed5i h\u00e0nh vi, ph\u1ea3n \u1ee9ng da, co gi\u1eadt, kh\u00ed, d\u1ec5 b\u1ecb k\u00edch th\u00edch v\u00e0 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1c.<\/p>\n

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3.2 Khi d\u00f9ng d\u01b0\u1edbi d\u1ea1ng ti\u00eam<\/h3>\n

Axit folic l\u00e0 an to\u00e0n cho h\u1ea7u h\u1ebft m\u1ecdi ng\u01b0\u1eddi khi ti\u00eam v\u00e0o c\u01a1 th\u1ec3. H\u1ea7u h\u1ebft ng\u01b0\u1eddi l\u1edbn kh\u00f4ng g\u1eb7p b\u1ea5t k\u1ef3 t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0o khi s\u1eed d\u1ee5ng v\u1edbi li\u1ec1u d\u01b0\u1edbi 1 mg m\u1ed7i ng\u00e0y.<\/p>\n

3.3 \u0110\u1ed1i v\u1edbi tr\u01b0\u1eddng h\u1ee3p thi\u1ebfu axit folic<\/h3>\n

Li\u1ec1u th\u00f4ng th\u01b0\u1eddng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh l\u00e0 250 mcg (microgam) \u0111\u1ebfn 1 mg (miligam) m\u1ed7i ng\u00e0y.<\/p>\n

3.4 D\u00f9ng trong ng\u0103n ng\u1eeba d\u1ecb t\u1eadt b\u1ea9m sinh c\u1ee7a n\u00e3o v\u00e0 c\u1ed9t s\u1ed1ng (d\u1ecb t\u1eadt b\u1ea9m sinh \u1ed1ng th\u1ea7n kinh)<\/h3>\n

Ph\u1ee5 n\u1eef c\u00f3 kh\u1ea3 n\u0103ng mang thai n\u00ean u\u1ed1ng 400 mcg\u00a0axit folic<\/b>\u00a0m\u1ed7i ng\u00e0y t\u1eeb th\u1ef1c ph\u1ea9m b\u1ed5 sung, v\u1edbi ph\u1ee5 n\u1eef \u0111ang mang thai th\u00ec con s\u1ed1 n\u00e0y l\u00e0 600 mcg. Ph\u1ee5 n\u1eef c\u00f3 ti\u1ec1n s\u1eed mang thai ph\u1ee9c t\u1ea1p do d\u1ecb t\u1eadt \u1ed1ng th\u1ea7n kinh th\u01b0\u1eddng m\u1ea5t 4 mg m\u1ed7i ng\u00e0y b\u1eaft \u0111\u1ea7u m\u1ed9t th\u00e1ng tr\u01b0\u1edbc v\u00e0 ti\u1ebfp t\u1ee5c \u0111\u1ebfn 3 th\u00e1ng sau khi th\u1ee5 thai.<\/p>\n

3.5 \u1ede nh\u1eefng ng\u01b0\u1eddi b\u1ec7nh th\u1eadn giai \u0111o\u1ea1n cu\u1ed1i<\/h3>\n

N\u1ed3ng \u0111\u1ed9 homocysteine \u200b\u200bcao c\u00f3 th\u1ec3 kh\u00f3 \u0111i\u1ec1u tr\u1ecb h\u01a1n, v\u00e0 li\u1ec1u 800 mcg \u0111\u1ebfn 40 mg m\u1ed7i ng\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng.<\/p>\n

3.6 C\u1ea3i thi\u1ec7n ph\u1ea3n \u1ee9ng v\u1edbi thu\u1ed1c \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m<\/h3>\n

S\u1eed d\u1ee5ng li\u1ec1u 200-500 mcg m\u1ed7i ng\u00e0y.<\/p>\n

3.7 \u0110\u1ec3 gi\u1ea3m \u0111\u1ed9c t\u00ednh g\u00e2y ra b\u1edfi thu\u1ed1c methotrexate<\/h3>\n

1 mg m\u1ed7i ng\u00e0y c\u00f3 l\u1ebd l\u00e0 \u0111\u1ee7, nh\u01b0ng c\u0169ng c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng t\u1edbi 5 mg m\u1ed7i ng\u00e0y.<\/p>\n

3.8 Ng\u0103n ng\u1eeba b\u1ec7nh v\u1ec1 m\u1eaft d\u1eabn \u0111\u1ebfn gi\u1ea3m th\u1ecb l\u1ef1c \u1edf ng\u01b0\u1eddi l\u1edbn tu\u1ed5i<\/h3>\n

S\u1eed d\u1ee5ng theo li\u1ec1u 2.5 mg axit folic, 1 mg vitamin B12 (cyanocobalamin) v\u00e0 50 mg vitamin B6 (pyridoxine) m\u1ed7i ng\u00e0y.<\/p>\n

3.9 \u0110\u1ed1i v\u1edbi b\u1ec7nh n\u01b0\u1edbu r\u0103ng \u1edf ph\u1ee5 n\u1eef mang thai<\/h3>\n

N\u01b0\u1edbc s\u00fac mi\u1ec7ng c\u00f3 ch\u1ee9a axit folic \u0111\u00e3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng hai l\u1ea7n m\u1ed7i ng\u00e0y, m\u1ed7i l\u1ea7n trong m\u1ed9t ph\u00fat.<\/p>\n<\/div>\n

4. T\u00e1c d\u1ee5ng ph\u1ee5 khi d\u1ee5ng vitamin B9<\/h2>\n
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Khi s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng v\u1edbi li\u1ec1u th\u00edch h\u1ee3p,\u00a0axit folic<\/b>\u00a0s\u1ebd an to\u00e0n cho c\u01a1 th\u1ec3. Tuy nhi\u00ean, n\u1ebfu s\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 g\u00e2y ra: bu\u1ed3n n\u00f4n, \u0103n m\u1ea5t ngon, c\u00e1u g\u1eaft, r\u1ed1i lo\u1ea1n gi\u1ea5c ng\u1ee7,… Nh\u1eefng ng\u01b0\u1eddi b\u1ecb d\u1ecb \u1ee9ng c\u00f3 th\u1ec3 c\u00f3 ph\u1ea3n \u1ee9ng v\u1edbi vi\u1ec7c\u00a0b\u1ed5 sung axit folic.<\/b>\u00a0D\u1ea5u hi\u1ec7u c\u1ea3nh b\u00e1o c\u1ee7a ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng bao g\u1ed3m: ph\u00e1t ban da, ng\u1ee9a, kh\u00f3 th\u1edf,…<\/p>\n

Axit folic d\u01b0 th\u1eeba \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua\u00a0n\u01b0\u1edbc ti\u1ec3u<\/b><\/a>. M\u1ed9t l\u01b0\u1ee3ng\u00a0folate<\/b>\u00a0cao c\u00f3 th\u1ec3 che gi\u1ea5u s\u1ef1 thi\u1ebfu h\u1ee5t\u00a0vitamin B12<\/b>\u00a0cho \u0111\u1ebfn khi t\u00e1c d\u1ee5ng th\u1ea7n kinh c\u1ee7a n\u00f3 tr\u1edf n\u00ean kh\u00f4ng th\u1ec3 \u0111\u1ea3o ng\u01b0\u1ee3c. \u0110i\u1ec1u n\u00e0y th\u01b0\u1eddng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c kh\u1eafc ph\u1ee5c b\u1eb1ng c\u00e1ch b\u1ed5 sung 100% gi\u00e1 tr\u1ecb h\u00e0ng ng\u00e0y c\u1ee7a c\u1ea3 axit folic v\u00e0 vitamin B12.<\/p>\n

Khi d\u00f9ng axit folic c\u00f9ng v\u1edbi vitamin B6 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 \u0111au tim \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed b\u1ec7nh tim; axit folic c\u00f9ng v\u1edbi\u00a0s\u1eaft<\/b><\/a>\u00a0c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 t\u1eed vong ho\u1eb7c c\u1ea7n \u0111i\u1ec1u tr\u1ecb t\u1ea1i b\u1ec7nh vi\u1ec7n \u1edf nh\u1eefng khu v\u1ef1c tr\u00ean th\u1ebf gi\u1edbi n\u01a1i b\u1ec7nh\u00a0s\u1ed1t r\u00e9t<\/b><\/a>\u00a0l\u00e0 ph\u1ed5 bi\u1ebfn.<\/p>\n

Tr\u01b0\u1eddng h\u1ee3p\u00a0thi\u1ebfu m\u00e1u do thi\u1ebfu vitamin B12<\/b>: U\u1ed1ng axit folic c\u00f3 th\u1ec3 che gi\u1ea5u thi\u1ebfu m\u00e1u do thi\u1ebfu vitamin B12 v\u00e0 tr\u00ec ho\u00e3n \u0111i\u1ec1u tr\u1ecb th\u00edch h\u1ee3p.<\/p>\n

R\u1ed1i lo\u1ea1n co gi\u1eadt: U\u1ed1ng b\u1ed5 sung axit folic c\u00f3 th\u1ec3 l\u00e0m cho c\u01a1n co gi\u1eadt t\u1ed3i t\u1ec7 h\u01a1n \u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ecb r\u1ed1i lo\u1ea1n co gi\u1eadt, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u1edf li\u1ec1u cao.<\/p>\n

M\u1ed9t s\u1ed1 ph\u1ea3n \u1ee9ng c\u00f3 th\u1ec3 g\u00e2y ra khi axit folic k\u1ebft h\u1ee3p v\u1edbi m\u1ed9t s\u1ed1 thu\u1ed1c kh\u00e1c, bao g\u1ed3m:<\/p>\n